Several facts about the spread of African swine fever virus through feed

African swine fever has hit, and our country's pig, veterinary and feed sectors are completely unprepared. In the short term, the popularity of African swine fever has caused everyone to panic. Our frontline breeders do not have a deep knowledge of biological virology. As a result, various companies and experts hope to help us with some knowledge of pig frontline personnel. However, due to different starting points, various theories and misunderstandings are full of our industry. Here, I share a few points from my point of view for your reference. I hope that everyone can speak with facts and data in the face of disasters. Clean up. 4K7 China Feed Industry Information Network - based on feed, serving animal husbandry

1. Can contaminated feed spread African swine fever? Contaminated feed can spread African swine fever. 4K7 China Feed Industry Information Network - based on feed, serving animal husbandry

a. Facts 1. African swine fever is mainly transmitted by mouth and nose. If the feed is contaminated with live virus, the pigs can be infected after the entrance or the nose. Water, dust particles, fecal particles, contaminated workers' clothes and shoes, truck-laden soil, and any purchased items can cause infection if they carry a live virus. 4K7 China Feed Industry Information Network - based on feed, serving animal husbandry

b. Facts 2, Kansas State University's research report clearly demonstrates that if a live virus is inoculated into the feed, a 10^4 HCD50 virus dose can cause infection in the herd. 4K7 China Feed Industry Information Network - based on feed, serving animal husbandry

2. Is feed an important route of transmission for African swine fever? Feed contamination is not a route for the spread of African swine fever. 4K7 China Feed Industry Information Network - based on feed, serving animal husbandry

a. Facts 1, the November press conference of the Ministry of Agriculture indicated that none of the 68 African swine fever cases that had been identified as being transmitted were caused by feed. At the time, there were three main routes of communication, such as transporting pigs, personnel, and feeding uncooked drowning water. I personally think this data is important and truly reflects the real problem. The real problem is epidemic prevention awareness and management. After the African pigs, the awareness of the epidemic prevention of the bosses of our breeding factories has been greatly improved, but management may still be a huge problem. How to manage the salary is too low to manage the rewards and punishments? How to ask for a bath but no hot water, how to let the workers have the willingness to implement in the northern winter? 4K7 China Feed Industry Information Network - based on feed, serving animal husbandry

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b. Fact 2, African swine fever will die rapidly in relatively dry feed ingredients at temperatures between 10 and 20 degrees. Dr. Scott Dee's experiments show a half-life of only 2 days in various feed ingredients. . Even if there is a certain amount of African swine fever virus in the finished feed, say 10^3TCID50 virus, after 20 days of placement (note that the placement temperature is important), the virus in the raw material can be reduced to 10^0TCID50. The raw materials mentioned here are dry raw materials, fermented materials and high-moisture feeds, and there is no existing data on the half-life. In general, viruses survive longer under humid conditions. 4K7 China Feed Industry Information Network - based on feed, serving animal husbandry

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c. Although the risk of the feed itself is not large, the feed car is a high risk factor. For the aquaculture plant, the feed supplier should be required to provide proof of the disinfection of the feed vehicle, and the requirements must not be stopped by other pig factories. 4K7 China Feed Industry Information Network - based on feed, serving animal husbandry

3. Is there only one African swine fever virus in the feed that can cause infection in the feed? Not 4K7 China Feed Industry Information Network - Based on feed, serving animal husbandry

The Kansas State University study clearly demonstrates that a viral dose of 10^4 HCD50 is required to infect African swine fever through feed. 4K7 China Feed Industry Information Network - based on feed, serving animal husbandry

4. Now everyone is reporting that there are many feed ingredients that are PCR positive. Does PCR positive mean that there is a big risk in the feed ? It is not the 4K7 China Feed Industry Information Network - based on feed, serving animal husbandry

a. Facts 1. Positive PCR of feed ingredients is a gene fragment that finds African swine fever in feed ingredients. Only the gene fragments are not infectious. For example, DNA fragments with only dinosaurs cannot replicate dinosaurs. The African swine fever virus is a DNA double helix virus, and we all know that the DNA of the double helix is ​​very stable in the environment. Dead viruses, or broken virus fragments, can persist in the environment for a long time, so we are likely to detect fragments of African swine fever in many things, but these fragments are not infectious. 4K7 China Feed Industry Information Network - based on feed, serving animal husbandry

b. Fact 2, African swine fever will die rapidly in relatively dry feed ingredients at temperatures between 10 and 20 degrees. Dr. Scott Dee's experiments show a half-life of only 2 days in various feed ingredients. . Even if there is a certain amount of African swine fever virus in the finished feed, say 10^3TCID50 virus, after 20 days of placement (note that the placement temperature is important), the virus in the raw material can be reduced to 10^0TCID50, so that Lost infectivity. 4K7 China Feed Industry Information Network - based on feed, serving animal husbandry

c. Fact 3: The latest study by Harbin Research shows that no live virus was isolated from 21 samples of PCR-positive plasma. Continuous feeding of PCR-positive dry plasma for 3 weeks of susceptible animals did not result in infection of African swine fever. This further demonstrates that PCR positive does not represent infectivity. 4K7 China Feed Industry Information Network - based on feed, serving animal husbandry

5. Is it necessary for me to granulate at a high temperature to ensure the safety of the feed? It is not the 4K7 China Feed Industry Information Network - based on feed, serving animal husbandry

a. Fact 1: High temperature and dryness can quickly inactivate African swine fever virus. But there is no experiment to prove that the 85-degree 3 minute that the feed mill has launched can completely kill the virus, not to mention that it is the only way to kill the virus. 4K7 China Feed Industry Information Network - based on feed, serving animal husbandry

b. Fact 2: African swine fever will die rapidly in relatively dry feed ingredients at temperatures between 10 and 20 degrees. Dr. Scott Dee's experiments show that the half-life in various feed ingredients is only 2 day. Even if there is a certain amount of African swine fever virus in the finished feed, say 10^3TCID50 virus, after 20 days of placement (note that the placement temperature is important), the virus in the raw material can be reduced to 10^0TCID50, so that Lost infectivity. 4K7 China Feed Industry Information Network - based on feed, serving animal husbandry

5. Does pig plasma cause rapid spread of African swine fever? Not 4K7 China Feed Industry Information Network - based on feed, serving livestock

a. Fact 1: The latest study by Harbin Institute of Research showed that no live virus was isolated from 21 samples of PCR-positive plasma, and no infection occurred after 3 weeks of feeding to susceptible animals. Harbin Research concluded that standard production can kill live viruses in the blood. 4K7 China Feed Industry Information Network - based on feed, serving animal husbandry

b. Fact 2: After the No. 64 document of the Ministry of Agriculture in September 2018, the feed enterprises completely abolished the use of pig plasma in pigs. So far, feed companies have ensured that they do not use homologous in order to gain full trust from the farm. Sexual raw materials, so the outbreak of African swine fever has nothing to do with the use of pig plasma. 4K7 China Feed Industry Information Network - based on feed, serving animal husbandry

6. Is the feed risky? The feed is risky. 4K7 China Feed Industry Information Network - Based on feed, serving animal husbandry

a. Blood products from infected pigs that are not regulated are at risk. 4K7 China Feed Industry Information Network - based on feed, serving animal husbandry

b. Corn on the roadside is risky. 4K7 China Feed Industry Information Network - based on feed, serving animal husbandry

c. Any feed ingredients used to transport the vehicle with the pig are at risk. 4K7 China Feed Industry Information Network - based on feed, serving animal husbandry

7. How to assess the risk of feed 4K7 China Feed Industry Information Network - based on feed, service animal husbandry

a. Origin assessment: 1. There is no risk of raw materials imported from countries without African swine fever. For example, blood products imported from countries without African swine fever are risk-free. 2. The raw materials produced in the endemic areas of African swine fever need to be evaluated one by one. 4K7 China Feed Industry Information Network - based on feed, serving animal husbandry

b. Raw material evaluation: 1. The main grain imported from the endemic areas of African swine fever should be evaluated for the production method. The main food for drying should be increased in time or further processed. 2. The by-products imported from the endemic areas of African swine fever should be evaluated for their production methods. There is a risk of cross-contamination of production and transportation. The drying time needs to be increased, or further high temperature treatment. 4K7 China Feed Industry Information Network - based on feed, serving animal husbandry

c. Supplier evaluation: 1. Production method. 2. Mode of transportation. 4K7 China Feed Industry Information Network - based on feed, serving animal husbandry

d. Detection: For high-risk materials, PCR detection can be used as a reference. Note that PCR positive does not mean that it is infectious. Negative PCR can rule out the risk. 4K7 China Feed Industry Information Network - based on feed, serving animal husbandry

8. How to reduce the risk of feed transmission. 4K7 China Feed Industry Information Network - based on feed, serving animal husbandry

a. Raw material control to reduce the risk of using raw materials. 4K7 China Feed Industry Information Network - based on feed, serving animal husbandry

b. High-temperature granulation 4K7 China Feed Industry Information Network - based on feed, serving animal husbandry

c. Finished material placed at room temperature 4K7 China Feed Industry Information Network - based on feed, serving animal husbandry

d. Some additives for feeding. Note that there must be a scientifically based additive. For example, lauric acid has some effect on the enveloped virus. It works at that dose. What role it needs to think about, please don't believe in the medicine. 4K7 China Feed Industry Information Network - based on feed, serving animal husbandry

In summary, the feed can infect African swine fever, but the risk of feed transmission is very low, which is not the reason for the current epidemic of African swine fever. There is no need to over-hype the risk of feed. There are very simple ways to reduce the risk of feed. 4K7 China Feed Industry Information Network - based on feed, serving animal husbandry

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