Comparison of several processes of purified water equipment
June 19 13:34:17, 2025
The Chinese Pharmacopoeia (2000 edition) defines purified water for pharmaceutical purposes as being obtained through distillation, ion exchange, reverse osmosis, or similar methods. This definition broadened the scope beyond just distillation, marking significant progress in the evolution of pharmaceutical water production in China. According to the Pharmacopoeia, water for injection is distilled purified water. Meanwhile, the United States Pharmacopeia has consistently acknowledged reverse osmosis (RO) as a legitimate method for producing injection water across its seven editions, reflecting growing trust in membrane technologies for pharmaceutical water production. Membrane-based water purification has become an inevitable trend in the advancement of pharmaceutical water technology.
Today, both domestic and international pharmaceutical companies predominantly employ ion exchange, reverse osmosis, or combined ion exchange-reverse osmosis systems to produce purified water, followed by distillation for injection water. Ion exchange remains popular for deep desalination due to its low initial cost and compact footprint. However, its environmental impact is considerable, as regeneration necessitates substantial amounts of acid and alkali. Reverse osmosis membranes effectively remove bacteria, pyrogens, viruses, and organic matter, achieving near-complete purification. Secondary reverse osmosis can eliminate the need for ion exchange resins, yet high salinity in raw water can lead to conductivity exceeding acceptable levels. Medical-grade pure water demands stringent quality standards, often requiring resistivity values above 15 megohms. To ensure the safety of such water, entire systems are constructed using stainless steel, and sterilization units are installed at critical points.
Our company leverages innovative techniques like reverse osmosis and EDI to tailor comprehensive high-purity water treatment solutions that meet diverse user needs, addressing requirements for pharmaceutical plant and hospital water production.
Water purification equipment typically follows one of these three primary processes:
1. Raw water → pressurization pump → multimedia filter → activated carbon filter → water softener → precision filter → reverse osmosis unit → intermediate tank → intermediate pump → ion exchanger → purified water tank → pure water pump → UV sterilizer → microporous filter → distribution point.
2. Raw water → pressurization pump → multimedia filter → activated carbon filter → water softener → precision filter → reverse osmosis → pH adjuster → intermediate tank → second-stage reverse osmosis (positively charged RO membrane surface) → purified water tank → pure water pump → UV sterilizer → microporous filter → distribution point.
3. Raw water → pressurization pump → multimedia filter → activated carbon filter → water softener → precision filter → reverse osmosis machine → intermediate tank → intermediate pump → EDI system → purified water tank → pure water pump → UV sterilizer → microporous filter → distribution point.
Each process has its own merits and drawbacks:
1. Ion exchange resin offers lower initial investment and space requirements but demands frequent regeneration, consuming significant acid and alkali, thereby harming the environment.
2. Reverse osmosis pre-treatment coupled with ion exchange equipment results in a higher initial cost but longer regeneration cycles for ion equipment, reducing acid and alkali usage compared to standalone ion resin methods. Yet, it still poses some environmental risks.
3. Reverse osmosis pre-treatment paired with an electro-deionization (EDI) device represents an economical and eco-friendly approach to ultrapure water production. This continuous process avoids acid and alkali regeneration, minimizing environmental harm. However, its upfront costs are significantly higher than the previous two options.
Huaibei Yuanyi Water Purification Technology Co., Ltd. specializes in industrial water treatment equipment, including single and dual-stage reverse osmosis systems, deionized water equipment, desalination systems, drinking water systems, mountain spring water processing, natural mineral water equipment, pure water systems, ultrapure water systems, high-purity water systems, EDI electrodialysis systems, pharmaceutical water purification equipment, barrel and bottle water production lines, barrel filling machines, three-in-one bottle lines, bucket cleaning and capping machines, bottle cap disinfection machines, air showers, air purifiers, cleanroom workbenches, lamp inspection boxes, laboratory equipment, QS-certified machinery, and water treatment chemical scale inhibitors.
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